{"id":3897,"date":"2015-06-19T19:51:18","date_gmt":"2015-06-19T19:51:18","guid":{"rendered":"http:\/\/hivcareconnect.com\/?page_id=3897"},"modified":"2016-12-15T22:38:01","modified_gmt":"2016-12-15T22:38:01","slug":"treatment-as-prevention","status":"publish","type":"page","link":"https:\/\/hivcareconnect.com\/treatment-as-prevention\/","title":{"rendered":"Treatment as Prevention"},"content":{"rendered":"<div id=\"themify_builder_content-3897\" data-postid=\"3897\" class=\"themify_builder_content themify_builder_content-3897 themify_builder\">\n    \t<!-- module_row -->\n\t<div  class=\"themify_builder_row module_row clearfix module_row_0 themify_builder_3897_row module_row_3897-0 tb_39af808\">\n\t    \t    <div class=\"row_inner col_align_top\" >\n\t\t\t<div  class=\"module_column tb-column col-full   first tb_3897_column module_column_0 module_column_3897-0-0 tb_08ky938\">\n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    <!-- module menu -->\n<div  class=\"module module-menu tb_hjr0103   mobile-menu-slide\" data-menu-style=\"mobile-menu-slide\" data-menu-breakpoint=\"0\" data-element-id=\"tb_hjr0103\">\n            \n    <div class=\"module-menu-container \"><ul id=\"menu-live-healthy-sub-menu\" class=\"ui nav menu-bar orange  \"><li id=\"menu-item-11974\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-11974\"><a href=\"https:\/\/hivcareconnect.com\/health-beyond-hiv\/\">Health Beyond HIV<\/a><\/li>\n<li id=\"menu-item-11506\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-11506\"><a href=\"https:\/\/hivcareconnect.com\/hiv-and-aging\/\">HIV and Aging<\/a><\/li>\n<li id=\"menu-item-9516\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-9516\"><a href=\"https:\/\/hivcareconnect.com\/hiv-innovation-in-illinois\/\">HIV Innovation in Illinois<\/a><\/li>\n<li id=\"menu-item-8458\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-8458\"><a 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rel=\"nofollow\" title=\"Share by email\" href=\"mailto:?subject=Treatment%20as%20Prevention&#038;body=Hey%20check%20this%20out:%20https%3A%2F%2Fhivcareconnect.com%2Fwp-json%2Fwp%2Fv2%2Fpages%2F3897\" style=\"font-size: 0px;width:24px;height:24px;margin:0;margin-bottom:10px\"><img loading=\"lazy\" decoding=\"async\" alt=\"mail\" title=\"Share by email\" class=\"synved-share-image synved-social-image synved-social-image-share\" width=\"24\" height=\"24\" style=\"display: inline;width:24px;height:24px;margin: 0;padding: 0;border: none;box-shadow: none\" src=\"https:\/\/hivcareconnect.com\/wp-content\/plugins\/social-media-feather\/synved-social\/image\/social\/regular\/48x48\/mail.png\" \/><\/a><\/p>    <\/div>\n<\/div>\n<!-- \/module text -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t    <!-- \/row_inner -->\n\t<\/div>\n\t<!-- \/module_row -->\n\t<\/div>\n<\/div>\n<!-- \/module template_part -->\n<!-- module text -->\n<div  class=\"module module-text tb_ugmi449    \">\n            <div  class=\"tb_text_wrap\">\n    <p>Treatment as prevention (TasP) has been recognized by UNAIDS as a \u201cgame-changing\u201d new way to look at decreasing the spread of HIV. TasP works by using antiretroviral treatment (ART) to reduce the HIV \u201cviral load,\u201d or the amount of HIV in the blood. A low viral load helps keep a person living with HIV healthy and greatly reduces the chance of HIV transmission to others.<\/p>\n<h3>The HPTN 052 study supporting TasP for people living with HIV<\/h3>\n<p>In the HPTN 052 study that began recruiting participants in 2005, researchers set out to measure the effect of TasP toward reducing the transmission of HIV from HIV-positive individuals to HIV-negative individuals. Originally designed to conclude in 2015, the study was stopped in 2011 when the results showed that patients who underwent TasP were up to 20 times less likely to infect their partners than people who were untreated.<\/p>\n<p>In 18 sites across three continents, 1736 serodiscordant couples \u2013 one HIV-positive and one HIV-negative \u2013 were enrolled in the study, most of them being heterosexual. The HIV-positive enrollee had to have a CD4 count between 350 and 550 to ensure a baseline level of HIV proteins in the blood of all participants. From there, 50 percent of participants started ART right away, and the other 50 percent started ART after their CD4 count fell below 250.<\/p>\n<p>The HPTN 052 study showed that early treatment started at CD4 counts between 350 and 550 reduced the risk of HIV transmission to an uninfected partner by at least 96 percent. The study\u2019s results were presented in Rome at the 2011 Sixth International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention and received a standing ovation. Professor Myron Cohen of University of North Carolina, who led the study, said the study provided \u201cimportant results to give to serodiscordant couples.\u201d However, he urged caution since the participants in the transmission study were only monitored for a median of 1.7 years. During this study, condom use was reported by 94 percent of HIV-positive individuals at baseline.<\/p>\n<p>The U.S. Department of Health and Human Services now recommends TasP ART to those living with HIV, regardless of their CD4 cell count, based in part from the findings of the HPTN 052 study. TasP has not been studied in populations such as men who have sex with men and injection drug users, and does not account for situations such as having unprotected sex or multiple partners. For these populations, <a href=\"http:\/\/hivcareconnect.com\/prep-pmtct-and-pep\/\">PrEP<\/a> may be the more appropriate treatment.<\/p>\n<p>The World Health Organization recommends that TasP be offered to those living with HIV who have uninfected partners, or to those who are living in a population with a high HIV presence. However, an individual must be willing to commit to TasP for it to work to its full potential.<\/p>\n<p>If TasP methods are used effectively, they could produce population-wide benefits. Since they are not 100 percent effective, however, those taking TasP should not engage in high-risk behaviors, such as having multiple sex partners or taking injectable drugs. When used in synchronization with good sexual and behavioral health practices including ART adherence, TasP can help prevent HIV transmission and lessen the amount of people affected by the epidemic.<\/p>\n<p>To learn more:<\/p>\n<p><a href=\"http:\/\/www.aidsmap.com\/The-HPTN-052-study\/page\/1847774\/\" target=\"_blank\">The HPTN 052 study (Aidsmap.com)<\/a><\/p>\n<p><a href=\"http:\/\/www.aidsmap.com\/Treatment-is-prevention-HPTN-052-study-shows-96-reduction-in-transmission-when-HIV-positive-partner-starts-treatment-early\/page\/1879665\/\" target=\"_blank\">Treatment is prevention: HPTN 052 shows 96% reduction in transmission when HIV-positive partner starts treatment early (Aidsmap.com).<\/a><\/p>\n    <\/div>\n<\/div>\n<!-- \/module text -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t<div  class=\"sub_column module_column col3-1  last sub_column_post_3897 sub_column_0-0-2-1 tb_gntk503\"> \n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    \n    <!-- module video -->\n    <div  class=\"module module-video tb_3bw8340 video-top   \">\n\t                <div class=\"video-wrap\">\n\n\t\t\t<div class=\"tb_video_overlay\" data-href=\"https:\/\/youtu.be\/BSl0mScmv3E\">\n\t\t\t\t<span class=\"tb_video_play\"><\/span>\n\t\t\t\t\t\t\t<\/div>\n\n        <\/div>\n        <!-- \/video-wrap -->\n\n            <\/div>\n    <!-- \/module video -->\n        <!-- module image -->\n    <div  class=\"module module-image tb_xf15095   image-top  \">\n\t                <div class=\"image-wrap\">\n                            <img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"768\" src=\"http:\/\/hivcareconnect.com\/wp-content\/uploads\/lsht_poster_masonia.jpg\" class=\" wp-post-image wp-image-2826\" title=\"lsht_poster_masonia\" alt=\"let&#039;s start talking poster\" srcset=\"https:\/\/hivcareconnect.com\/wp-content\/uploads\/lsht_poster_masonia.jpg 500w, https:\/\/hivcareconnect.com\/wp-content\/uploads\/lsht_poster_masonia-195x300.jpg 195w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/>            \n                        <\/div>\n            <!-- \/image-wrap -->\n        \n        \n        <\/div>\n    <!-- \/module image -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t<\/div><!-- \/themify_builder_sub_row -->\n\t\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t    <!-- \/row_inner -->\n\t<\/div>\n\t<!-- \/module_row -->\n\t<\/div>\n<!-- \/themify_builder_content -->\n","protected":false},"excerpt":{"rendered":"<p>Treatment as prevention (TasP) has been recognized by UNAIDS as a \u201cgame-changing\u201d new way to look at decreasing the spread of HIV. TasP works by using antiretroviral treatment (ART) to reduce the HIV \u201cviral load,\u201d or the amount of HIV in the blood. A low viral load helps keep a person living with HIV healthy<a class=\"more-link\" href=\"https:\/\/hivcareconnect.com\/treatment-as-prevention\/\">Read More<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3897","page","type-page","status-publish","hentry","has-post-title","no-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"_links":{"self":[{"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/pages\/3897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/comments?post=3897"}],"version-history":[{"count":3,"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/pages\/3897\/revisions"}],"predecessor-version":[{"id":4666,"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/pages\/3897\/revisions\/4666"}],"wp:attachment":[{"href":"https:\/\/hivcareconnect.com\/wp-json\/wp\/v2\/media?parent=3897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}